Acne in adolescence or adulthood is often badly experienced. Fortunately, different treatments exist, more or less effective, sometimes with side effects.
Recently the congress of the American Academy of Dermatology was held in Cincinnati for cincinnati dermatology .
The good news ?
All acne sufferers may be able to regain a sense of serenity with their skin, thanks to new therapeutic treatments such as, topical minocycline, topical sebum reduction reducers.
Sarecycline is in Phase 3 study. The benefit of this antibiotic is to have a narrower spectrum of activity and increased anti-inflammatory activity.
- Minocycline already existed in topical formulas but was difficult to apply to the skin because they were too occlusive. A Phase 2 trial published in JAAD 2016 showed that topical minocycline would have a superior action on placebo on inflammatory and non-inflammatory lesions after one application per day for 12 weeks.
Focus on the gel (BPX-01): the new formulation is completely solubilized, bioavailable in a hydrophilic gel, penetrating directly into the epidermis and pilosebaceous follicle, targeting sebum, ensuring effective absorption and penetration of the active ingredient (Minocycline).
Cincinnati dermatology treat all adult patients and also pediatric patient with skin disorders.
The new treatments for all people suffering from increased sebum production have been put forward.
- SB204, topical salting-out of nitric oxide. Why nitric oxide? Since this endogenous molecule has anti-microbial and anti-inflammatory activity. No microbial resistance to this molecule has yet been demonstrated.
DRM01: olumacostat glasaretil, a new molecule targeting ACC (acetyl coenzyme-A carboxylase), a key regulator of sebum production.
Before taking advantage of this research, do not forget that acne is not inevitable, the current treatments bring satisfactions, not forgetting that a good hygiene of life must be respected.